Skip to main content

PEPCID® vs ZANTAC®

PEPCID® is a Histamine-2 blocker (H2 blocker) with the active ingredient famotidine. Famotidine helps relieve heartburn by reducing the amount of acid in the stomach.

PEPCID® offers three main products that provide heartburn relief that you can take whenever you need. Original Strength PEPCID AC® and Maximum Strength PEPCID AC® contain an H2 blocker that works fast and helps control acid all day or all night.* PEPCID Complete® combines an H2 Blocker with an antacid that starts neutralizing acid in seconds, so it works even faster. Because the faster it starts relieving heartburn, the better.

PEPCID VS. ZANTAC PRODUCT COMPARISON CHART

PEPCID® (famotidine) was authorized for sale by Health Canada in 1996 for treatment and prevention of heartburn. It has been available over-the-counter in 10 mg and 20 mg strengths since 1996 and 2007, respectively.

PEPCID® AND ZANTAC® are approved for the same use. However, PEPCID® contains Famotidine. Unlike Zantac® and other OTC products that contain Ranitidine.

Product Original Strength PEPCID AC® product

Original Strength PEPCID AC®

Maximum Strength PEPCID AC® product

Maximum Strength PEPCID AC®

PEPCID COMPLETE® product

PEPCID COMPLETE®

Zantac Maximum Strength, 150mg, 50 tablets

ZANTAC®

Active ingredient Famotidine (Acid Reducer) Famotidine (Acid Reducer)

Famotidine (Acid Reducer)

Calcium Carbonate (Antacid)

Magnesium Hydroxide (Antacid)

Ranitidine (Acid Reducer)
How it works Reduces stomach acid production Reduces stomach acid production

Reduces stomach acid production

*Neutralizes stomach acid

Reduces stomach acid production
Relieves heartburn associated with acid indigestion and sour stomach

Yes

Yes

Yes

Yes

Prevents heartburn before it happens

Yes

Yes

Yes

Yes

Starts to work in seconds*

Yes

Form Tablet Tablet Chewable Tablet Tablet
Reduces acid production

Yes

Yes

Yes

Yes

*Starts to neutralize acid on contact ZANTAC® is a registered trademark of Sanofi Inc.

PEPCID VS. ZANTAC PRODUCT COMPARISON CHART

PEPCID® (famotidine) was authorized for sale by Health Canada in 1996 for treatment and prevention of heartburn. It has been available over-the-counter in 10 mg and 20 mg strengths since 1996 and 2007, respectively.

PEPCID® AND ZANTAC® are approved for the same use. However, PEPCID® contains Famotidine. Unlike Zantac® and other OTC products that contain Ranitidine.

Product Original Strength PEPCID AC® product

Original Strength PEPCID AC®

Active ingredient Famotidine (Acid Reducer)
How it works Reduces stomach acid production
Relieves heartburn associated with acid indigestion and sour stomach

Yes

Prevents heartburn before it happens

Yes

Starts to work in seconds*
Form Tablet
Reduces acid production

Yes

Product Maximum Strength PEPCID AC® product

Maximum Strength PEPCID AC®

Active ingredient Famotidine (Acid Reducer)
How it works Reduces stomach acid production
Relieves heartburn associated with acid indigestion and sour stomach

Yes

Prevents heartburn before it happens

Yes

Starts to work in seconds*
Form Tablet
Reduces acid production

Yes

Product PEPCID COMPLETE® product

PEPCID COMPLETE®

Active ingredient

Famotidine (Acid Reducer)

Calcium Carbonate (Antacid)

Magnesium Hydroxide (Antacid)

How it works

Reduces stomach acid production

*Neutralizes stomach acid

Relieves heartburn associated with acid indigestion and sour stomach

Yes

Prevents heartburn before it happens

Yes

Starts to work in seconds*

Yes

Form Chewable Tablet
Reduces acid production

Yes

Product Zantac Maximum Strength, 150mg, 50 tablets

ZANTAC®

Active ingredient Ranitidine (Acid Reducer)
How it works Reduces stomach acid production
Relieves heartburn associated with acid indigestion and sour stomach

Yes

Prevents heartburn before it happens

Yes

Starts to work in seconds*
Form Tablet
Reduces acid production

Yes

*Starts to neutralize acid on contact ZANTAC® is a registered trademark of Sanofi Inc.